Category: Projects
-
Use of Machine learning algorithm to identify emerging variants
The objective of this project is to test the proof-of-concept machine learning algorithm in different geographical locations and compare of SARS-CoV-2 virus evolution in different places.
-
Analysis of factors related to disease severity in hospitalized patients
The objective of this project is to identify the clades/subclades of influenza viruses and other factors associated with severity of disease using clinical and genomic data from hospitalized patients of GIHSN network.
-
Analysis of the mutations in influenza viruses and its association with disease severity
The objective of this project is to identify the mutations in influenza viruses from hospitalized patients in Lyon since 2018 which are associated with severity of disease.
-
EASIER-COHORT
Introduction: The EASIER-COHORT project aims to automatically create patient cohorts for epidemiological studies. It focuses on extracting information from patient electronic medical records to identify populations in need of influenza screening, using natural language processing techniques. The project will use the systematic influenza screening policy during the COVID-19 pandemic at Hospices Civils de Lyon (HCL)…
-
RSV severe infection risk stratification in a French 5-year birth cohort using machine learning
Respiratory Syncytial Virus (RSV) poses a substantial threat to infants, often leading to challenges in hospital capacity. With recent pharmaceutical developments to be used during the prenatal and perinatal periods aimed at decreasing the RSV burden, there is a pressing need to identify infants at risk of severe disease. Using machine learning techniques, the aim…
-
Evolution of respiratory viruses: the B/Yamagata virus lineage
A characteristic of respiratory viruses is their ability to continue circulating despite the accumulated population immunity due to infections, and in the case of influenza, the use of vaccines. A genetic bottlenecking due to case reduction during the COVID-19 pandemic has, however, resulted in reduced genetic diversity of influenza virus, which may greatly impact vaccine…